1: 4,4'-di-tert-butyl-2-bromobiphenyl With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: 2-bromofluoren-9-one in tetrahydrofuran; hexane T=-78°C; 3: With hydrogenchloride; acetic acid 1 h; Heating / reflux;

hydrogenchloride; acetic acid in water 1 h; Heating;

1.1: Mg; BrCH2CH2Br / diethyl ether / 8 h / Heating 1.2: diethyl ether / Heating 2.1: HCl; acetic acid / H2O / 1 h / Heating View Scheme