1: With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine in ethanol
T=70°C; 48 h;
2: With sodium hydroxide in dichloromethane; water
pH=9 - 10;
参考文献
ADDEX PHARMACEUTICALS SA
Patent: WO2005/44797 A1, 2005 ;
Location in patent: Page/Page column 80-81 ;
WO 2005/044797 A1
