5-氟-2-硝基苯甲酰氯合成路线 （共 16 条）
反应条件
2: platinum; ethanol / Hydrogenation View Scheme
参考文献
Fosdick; Blackwell
Journal of the American Chemical Society, 1944 , vol. 66, p. 1165
参考文献
Fosdick; Blackwell
Journal of the American Chemical Society, 1944 , vol. 66, p. 1165
反应条件
1: ammonia / 1,2-dichloro-ethane / 20 °C 2: palladium 10 on activated carbon; hydrogen / methanol View Scheme
参考文献
Hour, Mann-Jen; Yang, Jai-Sing; Chen, Tai-Lin; Chen, Kuan-Tin; Kuo, Sheng-Chu; Chung, Jing-Gung; Lu, Chi-Cheng; Chen, Chia-Yi; Chuang, Yi-Hsuan
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2709 - 2721
参考文献
Fosdick; Blackwell
Journal of the American Chemical Society, 1944 , vol. 66, p. 1165
参考文献
Fosdick; Blackwell
Journal of the American Chemical Society, 1944 , vol. 66, p. 1165
反应条件
1: 91 percent / H2SO4, HNO3 / 0 °C
2: oxalyl chloride / dimethylformamide
View Scheme
参考文献
Farmer, J.Dean; Rudnicki, Suzanne M.; Suggs, J.William
Tetrahedron Letters, 1988 , vol. 29, # 40 p. 5105 - 5108
反应条件
ammonium hydroxide in tetrahydrofuran; water
T=20°C;
参考文献
Dams, Gery Karel Julia; Vereycken, Inge; Van Acker, Koenraad Lodewijk August; Gustin, Emmanuel Marie Paul Ernest; Verschueren, Wim Gaston; Ohagen, Asa Catrine
Patent: US2010/280268 A1, 2010 ;
Location in patent: Page/Page column 46-47 ;
反应条件
triethylamine in dichloromethane
T=20°C; 5 h;
参考文献
Beccalli, Egle M.; Broggini, Gianluigi; Paladino, Giuseppe; Zoni, Caterina
Tetrahedron, 2005 , vol. 61, # 1 p. 61 - 68
反应条件
triethylamine in dichloromethane
T=20°C; 5 h;
参考文献
Beccalli, Egle M.; Broggini, Gianluigi; Paladino, Giuseppe; Zoni, Caterina
Tetrahedron, 2005 , vol. 61, # 1 p. 61 - 68
反应条件
1: 96 percent / triethylamine / CH2Cl2 / 5 h / 20 °C
2: 98 percent / NaH / tetrahydrofuran / 12 h / 30 - 35 °C
View Scheme
参考文献
Beccalli, Egle M.; Broggini, Gianluigi; Paladino, Giuseppe; Zoni, Caterina
Tetrahedron, 2005 , vol. 61, # 1 p. 61 - 68
