5-氟-2-甲氧基苯甲酸合成路线 (共 12 条)
反应条件
thionyl chloride; N,N-dimethyl-formamide in toluene
T=70°C; 1.5 h;
参考文献
Yu, Kuo-Long; Ruediger, Edward; Luo, Guangxiang; Cianci, Christopher; Danetz, Stephanie; Tiley, Laurence; Trehan, Ashok K.; Monkovic, Ivo; Pearce, Bradley; Martel, Alain; Krystal, Mark; Meanwell, Nicholas A.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 15 p. 2177 - 2180
反应条件
1: aqueous HBr; acetic acid
View Scheme
参考文献
Ostaszyuski,A. et al.
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1960 , vol. 8, p. 591 - 597