2,3,4,6-四-O-乙酰-β-D-吡喃葡萄糖合成路线 （共 199 条）
反应条件
in chloroform; ethyl acetate; Petroleum ether
参考文献
Ciba-Geigy Corporation
Patent: US5218097 A1, 1993 ;
反应条件
1: 97 percent / 1,2,4-triazole / CH2Cl2 / 2 h / Ambient temperature 2: 98 percent / 30percent H2O2 / tetrahydrofuran / 1.5 h / Ambient temperature 3: H2, 10percent NaHCO3 / 5percent Pd/C / ethanol / 10 h / 760.2 Torr / Ambient temperature 4: 1N NaOH / 3 h / Ambient temperature View Scheme
参考文献
Sim, Mui Mui; Kondo, Hirosato; Wong, Chi-Huey
Journal of the American Chemical Society, 1993 , vol. 115, # 6 p. 2260 - 2267
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / dichloromethane / 0 - 20 °C 2: iodine / acetonitrile / 25 °C View Scheme
参考文献
Jayasundara, Dilushan R.; Duff, Thomas; Angione, M. Daniela; Bourke, Jean; Murphy, Deirdre M.; Scanlan, Eoin M.; Colavita, Paula E.
Chemistry of Materials, 2013 , vol. 25, # 20 p. 4122 - 4128
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / dichloromethane / 0 - 20 °C 2: iodine / acetonitrile / 25 °C View Scheme
参考文献
Jayasundara, Dilushan R.; Duff, Thomas; Angione, M. Daniela; Bourke, Jean; Murphy, Deirdre M.; Scanlan, Eoin M.; Colavita, Paula E.
Chemistry of Materials, 2013 , vol. 25, # 20 p. 4122 - 4128
反应条件
2,4,6-trichloro-1,3,5-triazine; 1,8-diazabicyclo[5.4.0]undec-7-ene; N,N-dimethyl-formamide in 1,2-dichloro-ethane T=60°C; 2 h;
参考文献
Chang, Chih-Wei; Chang, Shih-Sheng; Chao, Chin-Sheng; Mong, Kwok-Kong T.
Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4536 - 4540
反应条件
in chloroform; ethyl acetate; Petroleum ether
参考文献
Ciba-Geigy Corporation
Patent: US5218097 A1, 1993 ;
反应条件
1: β-D-glucopyranose-2,3,4,6-tetraacetate With 1,4-diaza-bicyclo[2.2.2]octane in N,N-dimethyl-formamide T=20°C; deprotonation; 0.25 h; 2: 1-fluoro-2,4-dinitrobenzene in N,N-dimethyl-formamide T=20°C; Substitution; 2 h; Further stages.;
参考文献
Namchuk, Mark N.; McCarter, John D.; Becalski, Adam; Andrews, Trevor; Withers, Stephen G.
Journal of the American Chemical Society, 2000 , vol. 122, # 7 p. 1270 - 1277
反应条件
1,4-diaza-bicyclo[2.2.2]octane in N,N-dimethyl-formamide 2 h; Ambient temperature;
参考文献
Chittenden, Gordon J. F.
Carbohydrate Research, 1988 , vol. 183, p. 140 - 143
反应条件
15-crown-5; sodium hydride in dichloromethane Ambient temperature;
参考文献
Huchel, Ursula; Schmidt, Christoph; Schmidt, Richard R.
Tetrahedron Letters, 1995 , vol. 36, # 52 p. 9457 - 9460
反应条件
15-crown-5; sodium hydride in dichloromethane Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Huchel, Ursula; Schmidt, Christoph; Schmidt, Richard R.
Tetrahedron Letters, 1995 , vol. 36, # 52 p. 9457 - 9460
