5-甲基异恶唑-3-羰酰氯合成路线 （共 26 条）
参考文献
Dragovich, Peter S.; Prins, Thomas J.; Zhou, Ru; Johnnson JR., Theodore O.
Patent: US2001/47006 A1, 2001 ;
反应条件
1: aqueous NH3 2: P2O5 3: SnCl2; HCl; diethyl ether View Scheme
参考文献
Quilico; Panizzi
Gazzetta Chimica Italiana, 1938 , vol. 68, p. 625,635
反应条件
1: Et3N / toluene / Ambient temperature 2: 87 percent / LiAlH4 / tetrahydrofuran / 0 °C View Scheme
参考文献
Lepage; Tombret; Cuvier; Marivain; Gillardin
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 6 p. 581 - 593
反应条件
1: 75 percent / Et3N / toluene / 4 h / Heating
2: 45 percent / LiAlH4 / diethyl ether / 3 h / Heating
View Scheme
参考文献
Lepage; Tombret; Cuvier; Marivain; Gillardin
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 6 p. 581 - 593
反应条件
sodium azide in water; acetone
T=0 - 25°C; 1 h;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 43 ;
US 20030236287 A1
反应条件
triethylamine in acetonitrile
参考文献
Regel,E.; Buechel,K.-H.
Justus Liebigs Annalen der Chemie, 1977 , p. 145 - 158
