N-({[2-(3,5-二甲氧基苯基)-2-丙基]氧基}羰基)-L-丙氨酸合成路线 (共 1 条)
反应条件
1: Ddz-L-Ala-OH With 4-methyl-morpholine; isobutyl chloroformate in dichloromethane
T=-20°C; 1 h; Inert atmosphere;
2: 2-(2-bromo-3,5-dinitrophenyl)ethanamine hydrochloride With triethylamine in dichloromethane; N,N-dimethyl-formamide
T=20°C; Inert atmosphere;
参考文献
Debieux, Jean-Luc; Bochet, Christian G.
Journal of Organic Chemistry, 2009 , vol. 74, # 12 p. 4519 - 4524