(2E)-3-(2-噻吩基)丙烯醛合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in methanol; dichloromethane T=20°C; 0.5 h;
参考文献
Frere, Pierre; Raimundo, Jean-Manuel; Blanchard, Philippe; Delaunay, Jacques; Richomme, Pascal; Sauvajol, Jean-Louis; Orduna, Jesus; Garin, Javier; Roncali, Jean
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7254 - 7265
反应条件
1: 73 percent / diisopropylethylamine / 1,2-dichloro-ethane; CH2Cl2 / 3 h / -20 - 0 °C 2: 59 percent / xylene / 2.5 h / Heating 3: 59 percent / trifluoroacetic acid / Rh<P(C6H5)3>4H / ethanol / 2.5 h / Heating View Scheme
参考文献
Wiebe, Jennifer M.; Caille, Alain S.; Trimble, Laird; Lau, Cheuk K.
Tetrahedron, 1996 , vol. 52, # 36 p. 11705 - 11724
反应条件
1: 85 percent / KOH / ethanol / 0.25 h / Heating
2: 33 percent / 4 h / 650 °C / 0.01 Torr
View Scheme
参考文献
Hickson, Clare L.; McNab, Hamish
Synthesis, 1981 , # 6 p. 464 - 465
反应条件
sodium ethanolate in ethanol
1) RT, 2) 90 deg C;
参考文献
Spangler, Charles W.; Liu, Pei-Kang; Dembek, Alexa A.; Havelka, Kathleen O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 4 p. 799 - 802
反应条件
acetic anhydride; PbO
参考文献
Miller; Nord
Journal of Organic Chemistry, 1951 , vol. 16, p. 1380,1386
