2-羟基-4-甲氧基苯胺盐酸盐合成路线 （共 5 条）
反应条件
1: With sodium hydrogencarbonate in chloroform; water T=0°C; 2 h; 2: 3: With potassium carbonate in N,N-dimethyl-formamide T=85°C; 2 h;
参考文献
Goodman, Krista B.; Neeb, Michael J.; Sehon, Clark A.; Viet, Andrew Q.; Wang, Gren Z.
Patent: US2008/21023 A1, 2008 ;
Location in patent: Page/Page column 117 ;
US 20080021023 A1
反应条件
1.3-butanediol T=170°C; 2 h;
参考文献
Hoshi-Sakoda; Usui; Ishizuka; Kosemura; Yamamura; Hasegawa
Phytochemistry, 1994 , vol. 37, # 2 p. 297 - 300
反应条件
1: 2 percent / 0.42 h / 160 °C 2: 55 percent / 0.5 h / 165 °C View Scheme
参考文献
Nachman
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 5 p. 1423 - 1425
反应条件
triethylamine in dichloromethane T=20°C; 5 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/24182 A1, 2007 ;
Location in patent: Page/Page column 30 ;
WO 2007/024182 A1
反应条件
T=160°C; 0.416667 h;
参考文献
Nachman
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 5 p. 1423 - 1425
