2-氨基-4-甲基苯甲酰胺合成路线 （共 19 条）
反应条件
potassium hydroxide in ethanol 24 h; RefluxInert atmosphere;
参考文献
Cheng, Xu; Vellalath, Sreekumar; Goddard, Richard; List, Benjamin
Journal of the American Chemical Society, 2008 , vol. 130, # 47 p. 15786 - 15787
反应条件
hydrazine hydrate; nickel in ethanol T=60°C;
参考文献
Joshi, Vidya; Chaudhari, Rajendra P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 602 - 604
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Glenmark Pharmaceuticals S.A.; GHARAT, Laxmikant Atmaram; Banerjee, Abhisek; Khairatkar-Joshi, Neelima; Kattige, Vidya Ganapati
Patent: US2013/210844 A1, 2013 ;
Location in patent: Paragraph 0263; 0269; 0436; 0437 ;
反应条件
ammonium hydroxide in tetrahydrofuran; water T=0°C; 2 h;
参考文献
Kaniskan, Nevin; Koekten, Sule; Celik, Ilhami
Arkivoc, 2012 , vol. 2012, # 8 p. 198 - 213
反应条件
1.1: diphenylphosphoryl chloride; Et3N / CHCl3 1.2: NH3 2.1: H2 / 5 percent Pd/C / ethanol View Scheme
参考文献
Glenmark Pharmaceuticals S.A.; GHARAT, Laxmikant Atmaram; Banerjee, Abhisek; Khairatkar-Joshi, Neelima; Kattige, Vidya Ganapati
Patent: US2013/210844 A1, 2013 ;
反应条件
copper(l) iodide; sodium azide; ethanol; caesium carbonate T=20 - 95°C; Inert atmosphereSealed tube;
参考文献
Zhao, Haibo; Fu, Hua; Qiao, Renzhong
Journal of Organic Chemistry, 2010 , vol. 75, # 10 p. 3311 - 3316
反应条件
1: ammonium hydroxide / tetrahydrofuran / 4 h / 0 - 26 °C 2: iron; ammonium chloride / ethanol; water / 2 h / |Reflux View Scheme
参考文献
Glenmark Pharmaceuticals S.A.; GHARAT, Laxmikant Atmaram; Banerjee, Abhisek; Khairatkar-Joshi, Neelima; Kattige, Vidya Ganapati
Patent: US2013/210844 A1, 2013 ;
参考文献
Borsche; Herbert
Justus Liebigs Annalen der Chemie, 1941 , vol. 546, p. 277,291
反应条件
2: tin; concentrated hydrochloric acid / >60 View Scheme
参考文献
Morgan; Coulson
Journal of the Chemical Society, 1929 , p. 2557
参考文献
Morgan; Coulson
Journal of the Chemical Society, 1929 , p. 2557
