反应条件
1: 2-Iodo-benzoic acid ethyl ester With iso-propylmagnesium bromide in tetrahydrofuran
T=-40°C; 0.5 h; Inert atmosphere;
2: With copper (I) cyanide; lithium chloride in tetrahydrofuran
T=-40°C; 0.0833333 h; Inert atmosphere;
3: 2-chloro-3-iodopropene in tetrahydrofuran
T=-40 - 20°C; Inert atmosphere;
参考文献
Linghu, Xin; McLaughlin, Mark; Chen, Cheng-Yi; Reamer, Robert A.; Dimichele, Lisa; Davies, Ian W.
Tetrahedron Letters, 2012 , vol. 53, # 13 p. 1550 - 1552