5,7-二甲基[1,8]萘啶-2-胺合成路线 （共 8 条）
反应条件
sulfuric acid in acetic acid 24 h; Reflux;
参考文献
Li, Hui Fang Jie; Fu, Wen Fu
Chinese Chemical Letters, 2010 , vol. 21, # 1 p. 23 - 26
参考文献
Ochiai; Miyaki
Chemische Berichte, 1941 , vol. 74, p. 1115,1123
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Mangini; Colonna
Gazzetta Chimica Italiana, 1943 , vol. 73, p. 323,327
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Bernstein et al.
Journal of the American Chemical Society, 1947 , vol. 69, p. 1147,1148
反应条件
in ethanol 3 h; Heating;
参考文献
Gueiffier, A.; Blache, Y.; Viols, H.; Chapat, J. P.; Chavignon, O.; et al.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 283 - 287
反应条件
1: H2O / Diazotization
2: POCl3
View Scheme
参考文献
Gan, Xin; Chi, Shao-Ming; Mu, Wei-Hua; Yao, Jia-Can; Quan, Li; Li, Cong; Bian, Zhao-Yong; Chen, Yong; Fu, Wen-Fu
Dalton Transactions, 2011 , vol. 40, # 28 p. 7365 - 7374
反应条件
1: 67.8 percent / benzene / 3 h / Heating
2: 44 percent / Dowtherm A / 1 h / Heating
View Scheme
参考文献
Tonetti; Primofiore
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 12 p. 1052 - 1058
反应条件
dowtherm A
0.75 h; Heating;
参考文献
Tonetti; Primofiore
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 12 p. 1052 - 1058
反应条件
1: 67.8 percent / benzene / 3 h / Heating
2: 44 percent / Dowtherm A / 1 h / Heating
3: conc. ammonia / ethanol / 24 h / Heating
View Scheme
参考文献
Tonetti; Primofiore
Farmaco, Edizione Scientifica, 1980 , vol. 35, # 12 p. 1052 - 1058
反应条件
1: H2O / Diazotization
2: POCl3
3: palladium/CaCO3; palladium/charcoal; methanol. KOH / Hydrogenation
4: platinum; acetic acid / Hydrogenation
View Scheme
参考文献
Ochiai; Miyaki
Chemische Berichte, 1941 , vol. 74, p. 1115,1123
Full Text Show Details
Miyaki
Yakugaku Zasshi, 1942 , vol. 62, p. 26,35
Chem.Abstr., 1951 , p. 627
