咪唑并[1,2-a]吡啶-2-胺合成路线 （共 6 条）
反应条件
1: NaOH-solution; water View Scheme
参考文献
Masurier, Nicolas; Aruta, Roberta; Gaumet, Vincent; Denoyelle, Severine; Moreau, Emmanuel; Lisowski, Vincent; Martinez, Jean; Maillard, Ludovic T.
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3679 - 3685
反应条件
1: pyridine / 90 °C 2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 24 h / 20 °C 3: dichloromethane / 4 h / 0 - 20 °C 4: water; sodium hydroxide / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Masurier, Nicolas; Aruta, Roberta; Gaumet, Vincent; Denoyelle, Severine; Moreau, Emmanuel; Lisowski, Vincent; Martinez, Jean; Maillard, Ludovic T.
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3679 - 3685
反应条件
1: dichloromethane / 4 h / 0 - 20 °C 2: water; sodium hydroxide / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Masurier, Nicolas; Aruta, Roberta; Gaumet, Vincent; Denoyelle, Severine; Moreau, Emmanuel; Lisowski, Vincent; Martinez, Jean; Maillard, Ludovic T.
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3679 - 3685
反应条件
1: 85 percent / 3.5 h / Heating 2: 80 percent / aq. NaOH / 7 h / Heating View Scheme
参考文献
Chezal, Jean M; Moreau, Emmanuel; Chavignon, Olivier; Gaumet, Vincent; Metin, Jacques; Blache, Yves; Diez, Anna; Fradera, Xavier; Luque, Javier; Teulade, Jean C
Tetrahedron, 2002 , vol. 58, # 2 p. 295 - 307
反应条件
1: NaOH-solution; water View Scheme
参考文献
Bristow et al.
Journal of the Chemical Society, 1954 , p. 616,62O
参考文献
Bristow et al.
Journal of the Chemical Society, 1954 , p. 616,62O
