1-(4-甲基苯基)哌嗪合成路线 （共 31 条）
反应条件
1: 1.) O3 2.) NaBH3CN, CH3COOH / 1.)MeOH, CH2Cl2; -60 deg C; 2.) MeOH, -60 deg C, 10 min; 0 deg C for 20 h 2: K2CO3 / methanol; H2O / 20 h View Scheme
参考文献
Kawaguchi, Mamoru; Hayashi, Osamu; Kanamoto, Masahiro; Hamada, Masayuki; Yamamoto, Yukio; Oda, Jun'ichi
Agricultural and Biological Chemistry, 1987 , vol. 51, # 2 p. 435 - 440
参考文献
Prelog; Blazek
Collection of Czechoslovak Chemical Communications, 1934 , vol. 6, p. 211,218
参考文献
Fujii et al.
Yakugaku Zasshi, 1954 , vol. 74, p. 1049
Chem.Abstr., 1955 , p. 11666
参考文献
Pollard; Fernandez
Journal of Organic Chemistry, 1958 , vol. 23, p. 1935
反应条件
in water; N,N-dimethyl-formamide 1) heating, 10 min, 2) r.t., overnight;
参考文献
Agarwal
Journal of the Indian Chemical Society, 1991 , vol. 68, # 2 p. 85 - 87
反应条件
1: 75 percent / 48 h / 120 - 140 °C
2: 85 percent / hydrazin hydrate (98 percent) / Raney nickel / dimethylformamide / 10 h / Heating
3: 65 percent / benzene / 8 h / Heating
View Scheme
参考文献
Agarwal, Jagdish C.; Gupta, Y. K.; Bhargava, K. P.; Shanker, K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 6 p. 512 - 514
反应条件
Cu-nanoparticles in tetrahydrofuran
T=25°C; aza-Michael reaction; 8 h;
参考文献
Verma, Akhilesh K.; Kumar, Rupesh; Chaudhary, Preeti; Saxena, Amit; Shankar, Ravi; Mozumdar, Subho; Chandra, Ramesh
Tetrahedron Letters, 2005 , vol. 46, # 31 p. 5229 - 5232
参考文献
Agarwal; Misra; Satsangi; Tiwari
Archiv der Pharmazie, 1982 , vol. 315, # 2 p. 142 - 146
参考文献
Agarwal; Misra; Satsangi; Tiwari
Archiv der Pharmazie, 1982 , vol. 315, # 2 p. 142 - 146
参考文献
Agarwal; Misra; Satsangi; Tiwari
Archiv der Pharmazie, 1982 , vol. 315, # 2 p. 142 - 146
