反应条件
1.1: Et2Zn / CH2Cl2; hexane / 0.5 h / 0 °C
1.2: 76 percent / CH2Cl2; hexane / 2 h / 0 - 20 °C
2.1: 85 percent / (COCl)2; DMSO; Et3N / CH2Cl2 / -60 - 20 °C
3.1: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / 4 h / 160 °C
3.2: 75 percent / NaOH / bis-(2-hydroxy-ethyl) ether / 180 °C
4.1: 80 percent / H2; NaOAc / PtO2 / acetic acid / 192 h / 20 °C / 1216 - 1368 Torr
View Scheme
参考文献
Abad, Antonio; Agullo, Consuelo; Cunat, Ana C; Jimenez, Diego; Perni, Remedios H
Tetrahedron, 2001 , vol. 57, # 48 p. 9727 - 9735
