2-羟基-4-硝基苯甲酰氯合成路线 （共 12 条）
反应条件
1: pyridine 2: H2 / Pd/C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 5 p. 1749 - 1761
反应条件
1: pyridine; CHCl3 2: Raney nickel; dioxane / Hydrogenation View Scheme
参考文献
Clauder et al.
Magyar kem. LapjaChem.Abstr., 1949 , vol. 4, p. 596,601
Magyar kem. LapjaChem.Abstr., 1953 , p. 116
参考文献
Kaur, Gurmeet; Narayanan, Ven L.; Risbood, Prabhakar A.; Hollingshead, Melinda G.; Stinson, Sherman F.; Varma, Ravi K.; Sausville, Edward A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1749 - 1761
反应条件
1: pyridine 2: H2 / Pd/C 3: H2 / Pd/C View Scheme
参考文献
Kaur, Gurmeet; Narayanan, Ven L.; Risbood, Prabhakar A.; Hollingshead, Melinda G.; Stinson, Sherman F.; Varma, Ravi K.; Sausville, Edward A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1749 - 1761
反应条件
thionyl chloride in chloroform
T=0°C; 5 h; Heating / reflux;
参考文献
F2G LTD
Patent: WO2008/62182 A1, 2008 ;
Location in patent: Page/Page column 136 ;
反应条件
triethylamine in tetrahydrofuran
T=0 - 20°C;
参考文献
SCHERING AG
Patent: WO2005/89815 A2, 2005 ;
Location in patent: Page/Page column 29 ;
反应条件
2: ethanolic HCl
3: platinum; 2-methoxy-ethanol / Hydrogenation
View Scheme
参考文献
Godtfredsen et al.
Acta Chemica Scandinavica (1947-1973), 1953 , vol. 7, p. 781,782
反应条件
2: ethanolic HCl
3: platinum; 2-methoxy-ethanol / Hydrogenation
View Scheme
参考文献
Godtfredsen et al.
Acta Chemica Scandinavica (1947-1973), 1953 , vol. 7, p. 781,782
反应条件
2: iron-powder; aq.-ethanolic HCl
View Scheme
参考文献
Clauder et al.
Magyar kem. LapjaChem.Abstr., 1949 , vol. 4, p. 596,600
Magyar kem. LapjaChem.Abstr., 1953 , p. 116
反应条件
2: platinum; 2-methoxy-ethanol / Hydrogenation
View Scheme
参考文献
Godtfredsen et al.
Acta Chemica Scandinavica (1947-1973), 1953 , vol. 7, p. 781,782
