N-(2,6-二甲基苯基)-2-吡啶甲酰胺合成路线 （共 7 条）
反应条件
potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether in toluene T=120°C; P=7500.75 Torr; 18 h;
参考文献
Dang, Tuan T.; Zhu, Yinghuai; Ngiam, Joyce S. Y.; Ghosh, Subhash C.; Chen, Anqi; Seayad, Abdul M.
ACS Catalysis, 2013 , vol. 3, # 6 p. 1406 - 1410
反应条件
pyridine in dichloromethane T=-5 - 20°C;
参考文献
PHARMATHEN S.A.
Patent: WO2009/89842 A1, 2009 ;
Location in patent: Page/Page column 5 ;
反应条件
hydrogenchloride; sodium nitrite in water T=45°C; 40 h;
参考文献
Joergensen, K. A.; Ghattas, A.-B.A.G.; Lawesson, S.-O.
Tetrahedron, 1982 , vol. 38, # 9 p. 1163 - 1168
反应条件
triethylamine; trichlorophosphate in dichloromethane T=0°C; 2 h;
参考文献
Ju, Long; Yao, Jinzhong; Wu, Zaihong; Liu, Zhanxiang; Zhang, Yuhong
Journal of Organic Chemistry, 2013 , vol. 78, # 21 p. 10821 - 10831
反应条件
1,4-dioxane; triethylamine anschliessend Behandeln mit 2,6-Dimethyl-anilin;
参考文献
Rinderknecht
Helvetica Chimica Acta, 1959 , vol. 42, p. 1324,1326
反应条件
1: ethanol 2: platinum; aqueous acetic acid / Hydrogenation View Scheme
参考文献
Rinderknecht
Helvetica Chimica Acta, 1959 , vol. 42, p. 1324,1326
反应条件
hydrogen; nickel; acetic acid in methanol T=50°C; P=13446.2 Torr; Product distribution / selectivity;
参考文献
PHARMATHEN S.A.
Patent: WO2009/89842 A1, 2009 ;
Location in patent: Page/Page column 5-6 ;
