Alpha-羟甲基苯乙酸甲酯合成路线 （共 19 条）
反应条件
barium dihydroxide dl-tropic acid;
参考文献
Wislicenus; Bilhuber
Chemische Berichte, 1918 , vol. 51, p. 1237
反应条件
1: phenyl-acetic acid methyl ester With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran
T=-78°C; 1 h;
2: 1-Hydroxymethyl-1H-benzotriazole in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
1: phenyl-acetic acid methyl ester With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran
T=-78°C; 1 h;
2: 2-(hydroxymethyl)-1,3-isoindolinedione in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
sodium hydrogencarbonate; paraformaldehyde in dimethyl sulfoxide
参考文献
Ganes Chemicals Inc.
Patent: US5239121 A1, 1993 ;
反应条件
toluene-4-sulfonic acid in methanol
Heating / reflux;
参考文献
Huang, Yazhong; Hu, Shuanghua; Degnan, Andrew P.
Patent: US2006/20019 A1, 2006 ;
Location in patent: Page/Page column 9 ;
US 20060020019 A1
反应条件
toluene-4-sulfonic acid
18 h; Heating;
参考文献
Haigh, David; Jefcott, Lee J.; Magee, Katherine; McNab, Hamish
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 24 p. 2895 - 2900
反应条件
1: 2 percent / acetate buffer pH 5 / H2O / 168 h / 30 °C / Gluconobacter roseus IAM 1841
2: diethyl ether
View Scheme
参考文献
Ohta, Hiromichi; Tetsukawa, Hatsuki; Noto, Naoko
Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2400 - 2404
反应条件
in methanol; diethyl ether
参考文献
Govindachari,T.R.; Viswanathan,N.
Tetrahedron, 1970 , vol. 26, p. 715 - 719
反应条件
lead(IV) acetate; trifluoroacetic acid in benzene
T=60°C; 4 h;
参考文献
Novokreshchennykh, V. D.; Lukashova, E. A.; Mochalov, S. S.; Shabarov, Yu. S.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2022 - 2027
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2315 - 2321
反应条件
aluminium amalgam; water
参考文献
Chem. Werke Grenzach
Patent: DE302737 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 13, p. 278
Full Text Show Details
Wislicenus; Bilhuber
Chemische Berichte, 1918 , vol. 51, p. 1237
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Mueller,E.
Chemische Berichte, 1918 , vol. 51, p. 254
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v. Braun
Chemische Berichte, 1920 , vol. 53, p. 1409
Full Text Show Details
McKenzie; Wood
Journal of the Chemical Society, 1919 , vol. 115, p. 832
