4-苄氧基吲哚-2-羧酸合成路线 （共 13 条）
反应条件
1: ethanol
2: potassium ethylate; diethyl ether; toluene / Behandeln des Reaktionsprodukts in wss. NaOH mit Na2S2O4
View Scheme
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
反应条件
diethyl ether; potassium ethanolate; toluene
Behandeln des Reaktionsprodukts in wss. NaOH mit Na2S2O4;
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
反应条件
1: SOCl2, DMF / CH2Cl2 / 3 h / Ambient temperature
2: NH3 / CH2Cl2; diethyl ether / -20 °C
3: 83 percent / trifluoroacetic acid anhydride, pyridine / 2 h / 0 °C
4: 82 percent / ammonium formate / 5percent Pd/C / methanol / a) RT, 1 h, b) reflux
5: 75 percent / morpholine / 2.5 h / Heating
View Scheme
参考文献
Pitha, Josef; Buchowiecki, Wieslaw; Milecki, Jan; Kusiak, John W.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 4 p. 612 - 615
