甲基 4-(1H-吡唑-1-甲基)苯甲酸合成路线 （共 3 条）
反应条件
lithium hydroxide hydrate T=20°C; 18 h;
参考文献
Zhou, Dahui; Gross, Jonathan L.; Sze, Jean Y.; Adedoyin, Adedayo B.; Bowlby, Mark; Di, Li; Platt, Brian J.; Zhang, Guoming; Brandon, Nicholas; Comery, Thomas A.; Robichaud, Albert J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5957 - 5960
反应条件
[3,2-c]pyrazole; NaH in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; N,N-dimethyl-formamide
参考文献
Sumitomo Pharmaceuticals Company, Limited
Patent: EP1479384 A1, 2004 ;
反应条件
potassium carbonate in dimethyl sulfoxide
T=80°C; 72 h;
参考文献
Zhou, Dahui; Gross, Jonathan L.; Sze, Jean Y.; Adedoyin, Adedayo B.; Bowlby, Mark; Di, Li; Platt, Brian J.; Zhang, Guoming; Brandon, Nicholas; Comery, Thomas A.; Robichaud, Albert J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5957 - 5960
