T=90°C; 2 h;

1: pyridine, 4-dimethylaminopyridine (DMAP) / 2 h / bath 90 deg C 2: POCl3 / toluene / 5 h / Heating View Scheme

1: Et3N, DMAP / 1.) RT, 1 h, 2.) 90 deg C, 1 h 2: 91 percent / POCl3 / toluene / 2 h / Heating 3: 91 percent / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature View Scheme

1: Et3N, DMAP / 1.) RT, 1 h, 2.) 90 deg C, 1 h 2: 91 percent / POCl3 / toluene / 2 h / Heating 3: 91 percent / LiAlH4 / diethyl ether / 0.5 h / Ambient temperature 4: 91 percent / NaH / tetrahydrofuran / 12 h / Ambient temperature 5: 65 percent / aq. HCOOH / Ra-Ni alloy / 3 h / 100 °C View Scheme

1: pyridine, 4-dimethylaminopyridine (DMAP) / 2 h / bath 90 deg C 2: POCl3 / toluene / 5 h / Heating 3: 2N NaOH / ethanol / 0.5 h / Ambient temperature View Scheme

in dichloromethane 1 h;

sodium carbonate in water T=0 - 23°C;

in tetrahydrofuran; acetic acid (electrolysis);