(R)-3-羟基丁酸甲酯合成路线 (共 39 条)
反应条件
sulfuric acid in dichloromethane 48 h; Heating;
参考文献
Lindermann, Russell J.; Griedel, Brian D.
Journal of Organic Chemistry, 1991 , vol. 56, # 19 p. 5491 - 5493
反应条件
sulfuric acid in 1,2-dichloro-ethane 48 h; Heating;
参考文献
Seebach; Hoffmann; Kuhnle; Lengweiler
Helvetica Chimica Acta, 1994 , vol. 77, # 7 p. 2007 - 2034
反应条件
NaBO3*H2O in tetrahydrofuran; methanol; water T=20°C; 12 h; Inert atmosphere;
参考文献
Bonet, Amadeu; Gulyas, Henrik; Fernandez, Elena
Angewandte Chemie - International Edition, 2010 , vol. 49, # 30 p. 5130 - 5134
参考文献
Solladie, Guy; Almario, Antonio
Tetrahedron Letters, 1992 , vol. 33, # 18 p. 2477 - 2480
反应条件
peracetic acid; palladium diacetate; mercury(II) diacetate in acetic acid 2 h; Ambient temperature;
参考文献
Fleming, Ian; Kindon, Nicolas D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 4 p. 303 - 316
参考文献
Christen, Markus; Crout, David H. G.
Journal of the Chemical Society, Chemical Communications, 1988 , # 4 p. 264 - 266
反应条件
1: (+)-macrosphelide E With potassium carbonate in methanol T=20°C; 2: diazomethane in diethyl ether T=20°C; 2 h; Further stages.;
参考文献
Yamada; Iritani; Doi; Minoura; Ito; Numata
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 22 p. 3046 - 3053
反应条件
1: ZnCl2, HAl(iBu)2 / tetrahydrofuran / -78 °C 2: 90 percent / Raney Nickel View Scheme
参考文献
Solladie, Guy; Almario, Antonio
Tetrahedron Letters, 1992 , vol. 33, # 18 p. 2477 - 2480
反应条件
1: bakers' yeast / ethanol; H2O / 48 h / 30 °C 2: Raney Ni W-4 View Scheme
参考文献
Nakamura, Kaoru; Ushio, Kazutoshi; Oka, Shinzaburo; Ohno, Atsuyoshi; Yasui, Shinro
Tetrahedron Letters, 1984 , vol. 25, # 36 p. 3979 - 3982
反应条件
hydrogen; (S)-Ru-BINAP T=60°C; P=30002.4 Torr; 1 h; Product distribution; Further Variations:ReagentsSolvents;
参考文献
Wolfson, Adi; Vankelecom, Ivo F. J.; Jacobs, Pierre A.
Tetrahedron Letters, 2003 , vol. 44, # 6 p. 1195 - 1198