(R)-3-羟基丁酸甲酯合成路线 （共 39 条）
反应条件
1: Candida guilliermondii 2: 80 percent / Raney nickel View Scheme
参考文献
Christen, Markus; Crout, David H. G.
Journal of the Chemical Society, Chemical Communications, 1988 , # 4 p. 264 - 266
反应条件
sulfuric acid T=20°C; Title compound not separated from byproducts.;
参考文献
Yamada; Iritani; Doi; Minoura; Ito; Numata
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 22 p. 3046 - 3053
参考文献
Speranza, Giovanna; Dada, Giuseppe; Lunazzi, Ludovico; Gramatica, Paola; Manitto, Paolo
Phytochemistry (Elsevier), 1986 , vol. 25, # 9 p. 2219 - 2222
反应条件
hydrogen; palladium on activated charcoal in acetic acid Ambient temperature; Product distribution;
参考文献
Bachmann, Beat M.; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 12 p. 2430 - 2461
反应条件
air; cells of Geotrichum candidum IFO5767 in water T=30°C; 24 h; Product distribution;
参考文献
Nakamura, Kaoru; Fujii, Mikio; Ida, Yoshiteru
Tetrahedron Asymmetry, 2001 , vol. 12, # 22 p. 3147 - 3153
反应条件
in diethyl ether; water; ethyl acetate 0.25 h;
参考文献
Jaeger, Robert J. R.; Spiteller, Peter
Journal of Natural Products, 2010 , vol. 73, # 8 p. 1350 - 1354
参考文献
Quang, Dang Ngoc; Hashimoto, Toshihiro; Toyota, Masao; Asakawa, Yoshinori
Journal of Natural Products, 2003 , vol. 66, # 12 p. 1613 - 1614
反应条件
camphor-10-sulfonic acid in dichloromethane T=20°C; Etherification; 36 h;
参考文献
Li, Shukun; Xu, Rui; Bai, Donglu
Tetrahedron Letters, 2000 , vol. 41, # 18 p. 3463 - 3466
反应条件
ee = 95percent; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Genet, J. P.; Juge, S.; Mallart, S.
Tetrahedron Letters, 1988 , vol. 29, # 51 p. 6765 - 6768
反应条件
1: With potassium hydroxide in water T=0 - 20°C; 48 h; Inert atmosphere; 2: With hydrogenchloride in water pH=1; Inert atmosphere;
参考文献
Burghart-Stoll, Heike; Brueckner, Reinhard
European Journal of Organic Chemistry, 2012 , # 21 p. 3978 - 4017
