三乙基(2E)-3-甲基-4-膦酰巴豆酸酯合成路线 （共 9 条）
反应条件
potassium hydroxide; 18-crown-6 ether in benzene 3 h; Ambient temperatureeffect of concentration on the stereoselectivity; other aldehydes;
参考文献
Kryshtal', G. V.; Serebryakov, E. P.; Suslova, L. M.; Yanovskaya, L. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 6 p. 1280 - 1283
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 6 p. 1417 - 1421
参考文献
Kryshtal', G. V.; Serebryakov, E. P.; Suslova, L. M.; Yanovskaya, L. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, # 10 p. 2142 - 2146
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 10 p. 2377 - 2382
反应条件
in diethyl ether
Heating;
参考文献
Kozlowska,M.; Sobotka,W.
Polish Journal of Chemistry, 1978 , vol. 52, p. 347 - 352
参考文献
Machleidt,H.; Wessendorf,R.
Justus Liebigs Annalen der Chemie, 1964 , vol. 679, p. 20 - 26
反应条件
1: 67 percent / n-BuLi
2: 98 percent / HF; pyridine
3: 45 percent / (BrC6H4)3NSbCl6 / CH2Cl2 / 0.33 h / 20 °C
4: lutidine
5: LiAlH4
6: MnO2
7: NaOMe
8: Dowex 50W-X8 (H+)
9: 56 percent / NaOMe
10: 54 percent / TBAF; AcOH / 50 °C
View Scheme
参考文献
Yamano, Yumiko; Ito, Masayoshi
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 6 p. 780 - 782
反应条件
sodium hydride in tetrahydrofuran
16 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Schurtenberger, Heidi; Voegeli, Ulrich; Pfander, Hanspeter
Helvetica Chimica Acta, 1983 , vol. 66, # 7 p. 2346 - 2357
反应条件
(i) NaOMe, MeOH, DMF, (ii) /BRN= 2238058/; Multistep reaction;
参考文献
Jarolim; Sorm
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 4 p. 1070 - 1077
反应条件
(i) NaH, 1,2-dimethoxy-ethane, (ii) /BRN= 2236816/; Multistep reaction;
参考文献
Jarolim; Sorm
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 4 p. 1070 - 1077
反应条件
(i) NaH, 1,2-dimethoxy-ethane, (ii) /BRN= 2236807/; Multistep reaction;
参考文献
Jarolim; Sorm
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, # 4 p. 1070 - 1077
