2-氨基-4-羟基-6-甲基嘧啶合成路线 （共 33 条）
反应条件
potassium carbonate in neat (no solvent) T=140°C; 0.166667 h; Microwave irradiation;
参考文献
Radhakrishnan; Sharma, Namita; Kundu, Lal Mohan
RSC Advances, 2014 , vol. 4, # 29 p. 15087 - 15090
反应条件
sodium amide in 1,2,3,4-tetrahydro-naphthalene 24 h; Heating;
参考文献
Botta, M.; Angelis, F. De; Finizia, G.; Gambacorta, A.; Nicoletti, R.
Synthetic Communications, 1985 , vol. 15, p. 27 - 34
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; N,N-dimethyl-formamide Dehalogenation; Suzuki cross-coupling; 24 h; Heating;
参考文献
Hannah, Duncan R.; Sherer, Edward C.; Davies, Roy V.; Titman, Roger B.; Laughton, Charles A.; Stevens, Malcolm F. G.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 4 p. 739 - 750
参考文献
Curatolo
Gazzetta Chimica Italiana, 1890 , vol. 20, p. 585
反应条件
in ethanol; toluene 3 h; Heating;
参考文献
Singh, Kamaljit; Singh, Kawaljit; Balzarini, Jan
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 428 - 433
反应条件
sulfuric acid; sulfur trioxide
参考文献
Custelcean, Radu; Craciun, Liliana
Tetrahedron, 2000 , vol. 56, # 29 p. 5067 - 5075
参考文献
Watanabe, K. A.; Su, T.-L.; Pankiewicz, K. W.; Harada, K.
Heterocycles, 1984 , vol. 21, # 1 p. 289 - 307
反应条件
phosphorus; hydrogen iodide
参考文献
Matsukawa; Sirakawa
Yakugaku Zasshi, 1952 , vol. 72, p. 913
Chem.Abstr., 1953 , p. 6425
反应条件
1: alcohol; ammonia / im Rohr 2: concentrated hydriodic acid; red phosphorus View Scheme
参考文献
Gabriel; Colman
Chemische Berichte, 1899 , vol. 32, p. 2934
Chemische Berichte, 1902 , vol. 35, p. 1570
参考文献
Lacey
Journal of the Chemical Society, 1954 , p. 854,859
