2-氨基-4-羟基-6-甲基嘧啶合成路线 (共 33 条)
参考文献
Tsuda; Ogawa
Yakugaku Zasshi, 1950 , vol. 70, p. 73,75
Chem.Abstr., 1950 , p. 5323
参考文献
Michael
Journal fuer Praktische Chemie (Leipzig), 1894 , vol. <2> 49, p. 42
American Chemical Journal, 1887 , vol. 9, p. 220
参考文献
Tsuda; Ogawa
Yakugaku Zasshi, 1950 , vol. 70, p. 73,75
Chem.Abstr., 1950 , p. 5323
反应条件
in dimethylsulfoxide-d6 T=22 - 28°C; determined of intermediers by 13C nmr; Mechanism;
参考文献
Katritzky, Alan R.; Yousaf, Taher I.
Canadian Journal of Chemistry, 1986 , vol. 64, p. 2087 - 2093
反应条件
trichlorophosphate Heating;
参考文献
Savall, Brad M.; Chavez, Frank; Tays, Kevin; Dunford, Paul J.; Cowden, Jeffery M.; Hack, Michael D.; Wolin, Ronald L.; Thurmond, Robin L.; Edwards, James P.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2429 - 2439
参考文献
Gabriel; Colman
Chemische Berichte, 1899 , vol. 32, p. 2934
Chemische Berichte, 1902 , vol. 35, p. 1570
反应条件
1: 89 percent / conc. HNO3, conc. H2SO4 / 3 h / Ambient temperature 2: 91 percent / CH2Cl2 / 5 h / Ambient temperature 3: 60 percent / NaH / dimethylformamide / 1.) r.t., 1 h, 2.) r.t., 12 h 4: 86 percent / dimethylformamide / 12 h / Ambient temperature 5: 94 percent / aq. Na2S2O4 / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Taylor, Edward C.; Young, Wendy B.
Journal of Organic Chemistry, 1995 , vol. 60, # 24 p. 7947 - 7952
反应条件
sulfuric acid; nitric acid 0.75 h; Ambient temperature;
参考文献
Bowden, Keith; Bright, Andrew C.
Journal of Chemical Research, Miniprint, 1992 , # 2 p. 514 - 539
反应条件
potassium hydroxide; ethanol
参考文献
Hull
Journal of the Chemical Society, 1957 , p. 4845,4850
参考文献
Hull
Journal of the Chemical Society, 1957 , p. 4845,4850