2,6-二溴-4-氨基吡啶合成路线 （共 13 条）
反应条件
sodium hydroxide in ethanol; water
参考文献
Polychip Pharmaceuticals Pty Ltd; The University of Sydney
Patent: US5929082 A1, 1999 ;
US 5929082 A
反应条件
1: With trifluoroacetic acid; isopentyl nitrite T=20 - 85°C; 3.33 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
Almirall, S.A.; Vidal Juan, Bernat; Forns Berenguel, Maria Pilar; Castillo Mcquade, Marcos; Erra Sola, Montserrat; Mir Cepeda, Marta
Patent: EP2441755 A1, 2012 ;
Location in patent: Paragraph 0174 ;
反应条件
1: With sulfuric acid; nitric acid
T=0 - 20°C; 0.75 h;
2: With sulfuric acid
T=100°C; 0.75 h;
参考文献
ALTANA PHARMA AG
Patent: WO2005/26164 A1, 2005 ;
Location in patent: Page/Page column 44 ;
