2-苯基噁唑-4-羧酸乙酯合成路线 （共 36 条）
反应条件
iodine; triethylamine; triphenylphosphine in dichloromethane
T=20°C; 3 h;
参考文献
Khose, Goraksha; Shinde, Shailesh; Panmand, Anil; Kulkarni, Ravibhushan; Munot, Yogesh; Bandyopadhyay, Anish; Barawkar, Dinesh; Patil, Santoshkumar N.
Tetrahedron Letters, 2014 , vol. 55, # 16 p. 2671 - 2674
反应条件
palladium diacetate; caesium carbonate; 1,3-bis(2,4,6-trimethylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene in 1,4-dioxane
T=110°C; 18 h; Inert atmosphere;
参考文献
Verrier, Cecile; Martin, Thibaut; Hoarau, Christophe; Marsais, Francis
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7383 - 7386
反应条件
1.1: tert-butyl nitrite; CuCl2 / acetonitrile / 60 - 80 °C
1.2: 83 percent / conc. HCl / acetonitrile; CH2Cl2
2.1: 87 percent / Pd(PPh3)4; aq. K2CO3 / toluene / 1 h / 90 °C
View Scheme
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2003 , vol. 5, # 16 p. 2911 - 2914
反应条件
palladium diacetate in 1,4-dioxane
T=110°C; 18 h;
参考文献
Hoarau, Christophe; De Kerdaniel, Alexis Du Fou; Bracq, Nicolas; Grandclaudon, Pierre; Couture, Axel; Marsais, Francis
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8573 - 8577
反应条件
1: 100 °C
2: 83 percent / t-BuONO; CuCl2 / acetonitrile / 2 h / 80 °C
3: 87 percent / K2CO3 / Pd(PPh3)4 / H2O; toluene / 1 h / 90 °C
View Scheme
参考文献
Hodgetts, Kevin J.; Kershaw, Mark T.
Organic Letters, 2002 , vol. 4, # 17 p. 2905 - 2907
反应条件
Raney-Ni (W2) in ethanol
Reflux;
参考文献
Misra, Nimesh C.; Ila
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5195 - 5202
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
6 h; Heating;
参考文献
Badr, Mahmoud Zarif Amin; Aly, Morsy Mohamed; Fahmy, Atiat Mohamed; Mansour, Mansour Esmael Younis
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 6 p. 1844 - 1847
反应条件
1: ethoxycarbonylacetoamidine With PhI(ODNs)OH in acetonitrile
2 h; Heating;
2: benzamide in acetonitrile
10 h; Heating;
参考文献
Lee, Jong Chan; Kim, Sehyun; Lee, Yong Chan
Synthetic Communications, 2003 , vol. 33, # 9 p. 1611 - 1614
反应条件
palladium diacetate; caesium carbonate; tris-(o-tolyl)phosphine in carbonic acid diethyl ester
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Dong, Jia Jia; Roger, Julien; Verrier, Cecile; Martin, Thibaut; Le Goff, Ronan; Hoarau, Christophe; Doucet, Henri
Green Chemistry, 2010 , vol. 12, # 11 p. 2053 - 2063
反应条件
1: 69 percent / hydroxylamine hydrochloride, sodium acetate / ethanol / 4 h / Ambient temperature
2: 100 percent / triethylamine / 0.17 h / Ambient temperature
3: 22 percent / 0.02 h / 170 °C / other alkyl O-vinylcarbohydroximates, sugar lactoxime O-vinyl ethers
View Scheme
参考文献
Yokoyama, Masataka; Irie, Masakazu; Sujino, Keiko; Kagemoto, Tsukusi; Togo, Hideo; Funabashi, Masuo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 16 p. 2127 - 2134
