2-苯基噁唑-4-羧酸乙酯合成路线 （共 36 条）
反应条件
1: 76 percent / Lawesson's reagent / xylene / 5 h / Heating
2: 69 percent / hydroxylamine hydrochloride, sodium acetate / ethanol / 4 h / Ambient temperature
3: 100 percent / triethylamine / 0.17 h / Ambient temperature
4: 22 percent / 0.02 h / 170 °C / other alkyl O-vinylcarbohydroximates, sugar lactoxime O-vinyl ethers
View Scheme
参考文献
Yokoyama, Masataka; Irie, Masakazu; Sujino, Keiko; Kagemoto, Tsukusi; Togo, Hideo; Funabashi, Masuo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 16 p. 2127 - 2134
反应条件
palladium diacetate; potassium carbonate; [(t-Bu)3PH]BF4; 2,2,2-trimethylacetic acid in toluene
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
palladium diacetate; potassium carbonate; [(t-Bu)3PH]BF4 in 1,4-dioxane
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
palladium diacetate; potassium carbonate; [(t-Bu)3PH]BF4; 2,2,2-trimethylacetic acid in 1,4-dioxane
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
palladium diacetate; potassium carbonate; 2-dicyclohexylphosphino-1,1'-biphenyl; 2,2,2-trimethylacetic acid in 1,4-dioxane
T=110°C; 18 h; Inert atmosphere; regioselective reaction;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
Mercury(II) toluene-p-sulphonate
Cyclization; 0.0333333 h; microwave irradiation;
参考文献
Lee, Jong Chan; Song, In-Goul
Tetrahedron Letters, 2000 , vol. 41, # 31 p. 5891 - 5894
反应条件
1: 100 percent / Et3N / CH2Cl2 / Ambient temperature
2: 22 percent / 0.02 h / 170 °C
View Scheme
参考文献
Yokoyama; Sujino; Irie; Togo
Tetrahedron Letters, 1991 , vol. 32, # 49 p. 7269 - 7272
反应条件
1: 85.9 percent / 2 h / 80 - 90 °C
2: 70.7 percent / NBS, benzoyl peroxide / CCl4 / 6 h / Heating
View Scheme
参考文献
Badr, Mahmoud Zarif Amin; Aly, Morsy Mohamed; Fahmy, Atiat Mohamed; Mansour, Mansour Esmael Younis
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 6 p. 1844 - 1847
反应条件
1: 85.9 percent / 2 h / 80 - 90 °C
2: 70.7 percent / NBS, benzoyl peroxide / CCl4 / 6 h / Heating
View Scheme
参考文献
Badr, Mahmoud Zarif Amin; Aly, Morsy Mohamed; Fahmy, Atiat Mohamed; Mansour, Mansour Esmael Younis
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 6 p. 1844 - 1847
反应条件
dirhodium tetraacetate
T=70°C; 6 h;
参考文献
Connell, Richard D.; Tebbe, Mark; Helquist, Paul; Akermark, Bjoern
Tetrahedron Letters, 1991 , vol. 32, # 1 p. 17 - 20
