2-溴-3-氨基吡啶合成路线

参考文献

Saari, Walfred S.; Halczenko, Wasyl; Huff, Joel R.; Guare, James P.; Hunt, Cecilia A.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 9 p. 1182 - 1185

39856-58-12-溴-3-氨基吡啶

452972-12-22-溴-3-吡啶基硼酸频哪醇酯

参考文献

Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain
Tetrahedron, 2002 , vol. 58, # 17 p. 3323 - 3328

39856-58-12-溴-3-氨基吡啶+

3282-30-2三甲基乙酰氯

835882-02-5N-(2-溴吡啶-3-基)三甲基乙酰胺

参考文献

JANSSEN PHARMACEUTICA, N.V.
Patent: WO2005/9967 A2, 2005 ;
Location in patent: Page/Page column 25-26 ;
WO 2005/009967 A2

39856-58-12-溴-3-氨基吡啶

272-49-14-氮杂吲哚

参考文献

Sakamoto, Takao; Kondo, Yoshinori; Iwashita, Shigeki; Yamanaka, Hiroshi
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 5 p. 1823 - 1828

39856-58-12-溴-3-氨基吡啶

7689-62-52-氯-1,5-萘啶

参考文献

AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;

39856-58-12-溴-3-氨基吡啶

6298-19-73-氨基-2-氯吡啶

参考文献

Berrie et al.
Journal of the Chemical Society, 1952 , p. 2042,2044

39856-58-12-溴-3-氨基吡啶+

140-89-6乙基黄原酸钾

57135-09-8吡啶并[3,2-D][1,3]噻唑-2-硫醇

参考文献

AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;
Location in patent: Paragraph 0654 ;

39856-58-12-溴-3-氨基吡啶

10261-82-22-羟基-1,5-萘啶

参考文献

AMGEN INC.; Allen, Jennifer R.; Amegadzie, Albert; Andrews, Kristin L.; Brown, James; Chen, Jian J.; Chen, Ning; Harrington, Essa Hu; Liu, Qingyian; Nguyen, Thomas T.; Pickrell, Alexander J.; Qian, Wenyuan; Rumfelt, Shannon; Rzasa, Robert M.; Yuan, Chester Chenguang; Zhong, Wenge
Patent: US2013/225552 A1, 2013 ;

39856-58-12-溴-3-氨基吡啶+

24424-99-5二碳酸二叔丁酯

116026-98-3(2-溴-3-吡啶基)氨基甲酸叔丁酯

参考文献

Kowol, Christian R.; Trondl, Robert; Heffeter, Petra; Arion, Vladimir B.; Jakupec, Michael A.; Roller, Alexander; Galanski, Markus; Berger, Walter; Keppler, Bernhard K.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 16 p. 5032 - 5043

39856-58-12-溴-3-氨基吡啶+

1538-75-6三甲基乙酸酐

116026-98-3(2-溴-3-吡啶基)氨基甲酸叔丁酯

参考文献

AMIRA PHARMACEUTICALS, INC.
Patent: WO2009/140642 A2, 2009 ;
Location in patent: Page/Page column 85 ;
WO 2009/140642 A2