hydrogen

<b>Multi-step reaction with 2 steps<br /> </b>1: 1.) 15 percent butyllithium / 1.) hexane, THF, -78 deg C, 30 min; 2.) -78 deg C, 1 h, r.t., 4 h<br />2: 68 percent / hydrogen, boric acid / Raney Ni W-2 / ethanol; CH₂Cl₂; H₂O / 48 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1.1: potassium carbonate / acetonitrile / 4 h / 20 &deg;C<br />2.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 3 h / 20 &deg;C<br />2.2: 3 h / 0 &deg;C<br />3.1: silver nitrate; sodium nitrite / water / 10 h / 20 &deg;C / Darkness<br />4.1: 4-(N,N-dimethlyamino)pyridine; acetic anhydride / dichloromethane / 20 &deg;C / Inert atmosphere<br />5.1: water; hydrogen / ethanol / 6 h / 1551.49 Torr<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 3 h / 20 &deg;C<br />1.2: 3 h / 0 &deg;C<br />2.1: silver nitrate; sodium nitrite / water / 10 h / 20 &deg;C / Darkness<br />3.1: 4-(N,N-dimethlyamino)pyridine; acetic anhydride / dichloromethane / 20 &deg;C / Inert atmosphere<br />4.1: water; hydrogen / ethanol / 6 h / 1551.49 Torr<br /> <br /> &nbsp;