(4-甲氧基苯乙炔基)三甲基硅烷合成路线 （共 73 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); copper(l) chloride in N,N-dimethyl-formamide
T=80°C; cross-coupling;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
反应条件
copper(l) iodide; [PdCl2(2,2'-bipyridine)]; cyclohexyl BrettPhos in N,N-dimethyl-formamide
T=150°C; 24 h;
参考文献
Nishihara, Yasushi; Ogawa, Daisuke; Noyori, Shintaro; Iwasaki, Masayuki
Chemistry Letters, 2012 , vol. 41, # 11 p. 1503 - 1505
反应条件
copper(l) iodide; [PdCl2(2,2'-bipyridine)]; cyclohexyl BrettPhos in N,N-dimethyl-formamide
T=120°C; 24 h;
参考文献
Nishihara, Yasushi; Ogawa, Daisuke; Noyori, Shintaro; Iwasaki, Masayuki
Chemistry Letters, 2012 , vol. 41, # 11 p. 1503 - 1505
反应条件
1: aq. KOH / methanol
2: 42 percent / PPh3; Et3N / PdCl2; CuI / benzene / 45 - 49 °C
View Scheme
参考文献
Vasil'ev; Rudenko; Grinenko
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 8 p. 1157 - 1162
反应条件
1: carbon monoxide; Sb(o-tolyl)3 With [bis(acetoxy)iodo]benzene in dichloromethane
T=20°C; 7 h;
2: 2-(4-methoxyphenyl)-1-trimethylsilyl-ethyne With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(l) iodide in acetonitrile
T=50°C; 5 h; Further stages.;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Hong, Young-Taek
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 7 p. 736 - 739
反应条件
1: methanol; potassium hydroxide / water / 12 h / 0 - 25 °C / Darkness; Inert atmosphere
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 2 h / 25 °C / Inert atmosphere
View Scheme
参考文献
Teiber, Marco; Mueller, Thomas J. J.
Chemical Communications, 2012 , vol. 48, # 15 p. 2080 - 2082
反应条件
copper(l) chloride in N,N-dimethyl-formamide
T=60°C; homo-coupling; 12 h;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
反应条件
copper(l) iodide; tetrabutyl ammonium fluoride; potassium carbonate; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=20°C; 2 h; Product distribution; Further Variations:CatalystsReaction partnersReagents;
参考文献
Girard, Delphine; Broussous, Sylvie; Provot, Olivier; Brion, Jean-Daniel; Alami, Mouad
Tetrahedron Letters, 2007 , vol. 48, # 34 p. 6022 - 6026
反应条件
copper trifluoromethanesulfonate in N,N-dimethyl-formamide
T=80°C; 48 h;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Mori, Atsunori; Hiyama, Tamejiro
Tetrahedron Letters, 1998 , vol. 39, # 23 p. 4075 - 4078
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) chloride in N,N-dimethyl-formamide
T=80°C; coupling; 24 h; Product distribution; Further Variations:Reagentsreagent ratios, reaction times;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
