2-[(三甲基甲硅烷基)乙炔基]甲苯合成路线 （共 10 条）
反应条件
copper(l) iodide; diisopropylamine; bis(benzonitrile)palladium(II) dichloride in 1,4-dioxane T=20°C; Sonogashira coupling;
参考文献
Hill, Lensey L.; Smith, Joanna M.; Brown, William S.; Moore, Lucas R.; Guevera, Paul; Pair, Emily S.; Porter, Jake; Chou, Joe; Wolterman, Christopher J.; Craciun, Raluca; Dixon, David A.; Shaughnessy, Kevin H.
Tetrahedron, 2008 , vol. 64, # 29 p. 6920 - 6934
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in N,N-dimethyl-formamide T=50°C; 6 h; Inert atmosphere;
参考文献
Sugimoto, Kenji; Hayashi, Rie; Nemoto, Hideo; Toyooka, Naoki; Matsuya, Yuji
Organic Letters, 2012 , vol. 14, # 13 p. 3510 - 3513
反应条件
copper(l) iodide; diethylamine; bis-triphenylphosphine-palladium(II) chloride T=20°C; Sonogashira reaction; 5 h;
参考文献
Koumbis, Alexandros E.; Kyzas, Christos M.; Savva, Antri; Varvoglis, Anastasios
Molecules, 2005 , vol. 10, # 10 p. 1340 - 1350
反应条件
sodium hydroxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-benzyl-N,N,N-triethylammonium chloride in benzene T=40°C; 48 h;
参考文献
D'Auria
Synthetic Communications, 1992 , vol. 22, # 16 p. 2393 - 2399
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine in tetrahydrofuran T=60°C; Sonogashira Cross-Coupling; Inert atmosphere;
参考文献
Atienza; Mateo; de Frutos; Echavarren
Organic letters, 2001 , vol. 3, # 2 p. 153 - 155
反应条件
tetrakis(triphenylphosphine) palladium(0)
参考文献
Luo, Fen-Tair; Wang, Ren-Tzong
Tetrahedron Letters, 1992 , vol. 33, # 45 p. 6835 - 6838
反应条件
1: potassium carbonate / methanol / 3 h / 20 °C 2: tetrakis(triphenylphosphine) palladium(0); hydrogenchloride / tetrahydrofuran; water / 168 h / 45 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Xu, Caixia; Du, Weiyuan; Zeng, Yi; Dai, Bin; Guo, Hao
Organic Letters, 2014 , vol. 16, # 3 p. 948 - 951
反应条件
potassium carbonate in methanol T=20°C; 3 h;
参考文献
Xu, Caixia; Du, Weiyuan; Zeng, Yi; Dai, Bin; Guo, Hao
Organic Letters, 2014 , vol. 16, # 3 p. 948 - 951
反应条件
water; triethylamine; triphenylphosphine; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in tetrahydrofuran T=160°C; P=51485.6 Torr; 4 h;
参考文献
Takeuchi, Ryo; Yasue, Hiroyuki
Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5386 - 5392
反应条件
1: tetrabutyl ammonium fluoride / tetrahydrofuran / -78 - 20 °C / Inert atmosphere
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 120 h / Inert atmosphere
View Scheme
参考文献
Weisheit, Thomas; Escudero, Danie; Petzold, Holm; Goerls, Helmar; Gonzalez, Leticia; Weigand, Wolfgang
Dalton Transactions, 2010 , vol. 39, # 40 p. 9493 - 9504
