2,4-二羟基吡咯[2,3-d]嘧啶合成路线

参考文献

Chen, Zecheng; Venkatesan, Aranapakam M.; Dehnhardt, Christoph M.; Ayral-Kaloustian, Semiramis; Brooijmans, Natasja; Mallon, Robert; Feldberg, Larry; Hollander, Irwin; Lucas, Judy; Yu, Ker; Kong, Fangming; Mansour, Tarek S.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 8 p. 3169 - 3182

52133-67-22-氰基-4,4-二乙氧基丁酸乙酯+

57-13-6尿素

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

参考文献

Xie, Hui; Zeng, Lili; Zeng, Shaogao; Lu, Xin; Zhang, Guicheng; Zhao, Xin; Cheng, Na; Tu, Zhengchao; Li, Zhiyuan; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Huang, Min; Zhao, Junling; Hu, Wenhui
European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 205 - 212

102879-75-46-氨基-5-(2,2-二乙氧基乙基)-2,4(1H,3H)-嘧啶二酮

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

参考文献

VERNALIS (R and D) LTD.
Patent: WO2007/104944 A1, 2007 ;
Location in patent: Page/Page column 38 ;

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

参考文献

The Upjohn Company
Patent: US5502187 A1, 1996 ;

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

60129-59-1（2R，3S，5R）-5-（4-氨基-7H-吡咯[2,3-D]嘧啶-7-基-2 -（羟甲基）四氢呋喃-3-醇

参考文献

Kazimierczuk, Zygmunt; Cottam, Howard B.; Revankar, Ganapathi R.; Robins, Roland K.
Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6379 - 6382

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

90213-66-42,4-二氯-7H-吡咯并[2,3-d]嘧啶

参考文献

Xie, Hui; Zeng, Lili; Zeng, Shaogao; Lu, Xin; Zhang, Guicheng; Zhao, Xin; Cheng, Na; Tu, Zhengchao; Li, Zhiyuan; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Huang, Min; Zhao, Junling; Hu, Wenhui
European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 205 - 212

56473-10-0+

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

90213-66-42,4-二氯-7H-吡咯并[2,3-d]嘧啶

参考文献

The Upjohn Company
Patent: US5502187 A1, 1996 ;

39929-79-82,4-二羟基吡咯[2,3-d]嘧啶

90213-67-52,4-二氯-7-甲基-7H-吡咯并[2,3-d]嘧啶

参考文献

Xie, Hui; Zeng, Lili; Zeng, Shaogao; Lu, Xin; Zhang, Guicheng; Zhao, Xin; Cheng, Na; Tu, Zhengchao; Li, Zhiyuan; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Huang, Min; Zhao, Junling; Hu, Wenhui
European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 205 - 212