1-CBZ-2-(2-羟乙基)哌啶合成路线 （共 4 条）
反应条件
1: 99 percent / imidazole, 4-(dimethylamino)pyridine / dimethylformamide / 0.5 h / Ambient temperature 2: 95 percent / H2 / 10percent Pd/C / methanol / 16 h / 760 Torr View Scheme
参考文献
Ndungu, J. Maina; Krumm, Stefanie A.; Yan, Dan; Arrendale, Richard F.; Reddy, G. Prabhakar; Evers, Taylor; Howard, Randy; Natchus, Michael G.; Saindane, Manohar T.; Liotta, Dennis C.; Plemper, Richard K.; Snyder, James P.; Sun, Aiming
Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4220 - 4230
反应条件
potassium carbonate in ethanol; water
T=0 - 20°C; 3.25 h;
参考文献
Rouchaud, Anne; Braekman, Jean-Claude
European Journal of Organic Chemistry, 2009 , # 16 p. 2666 - 2674
反应条件
in 1,4-dioxane; water
T=25°C; 24 h;
参考文献
Gomez, Livia; Garrabou, Xavier; Joglar, Jesus; Bujons, Jordi; Parella, Teodor; Vilaplana, Cristina; Cardona, Pere Joan; Clapes, Pere
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6309 - 6321
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione
参考文献
Gomez, Livia; Garrabou, Xavier; Joglar, Jesus; Bujons, Jordi; Parella, Teodor; Vilaplana, Cristina; Cardona, Pere Joan; Clapes, Pere
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 31 p. 6309 - 6321
