N-甲基-N-(3-甲基苯基)-甲酰胺合成路线 （共 10 条）
反应条件
water Heating; Yield given;
参考文献
Mossi, Waldo; Klaus, Alfred J.; Rys, Paul
Helvetica Chimica Acta, 1992 , vol. 75, # 8 p. 2531 - 2537
反应条件
sodium hydroxide in water T=30°C; also aq. DMSO; Rate constantMechanism;
参考文献
Bowden, Keith; Bromley, Keith
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1990 , p. 2103 - 2109
反应条件
1: conc. HCl / H2O / 2.5 h / 100 °C 2: 2.5 percent / aq. NaNO2, conc. HCl / 0 - 5 °C View Scheme
参考文献
Mossi, Waldo; Klaus, Alfred J.; Rys, Paul
Helvetica Chimica Acta, 1992 , vol. 75, # 8 p. 2531 - 2537
反应条件
indium
T=70°C; 6 h; neat (no solvent);
参考文献
Kim, Joong-Gon; Jang, Doo Ok
Synlett, 2010 , # 8 art. no. U00810ST, p. 1231 - 1234
反应条件
TEMPO; oxygen in acetonitrile
T=50°C; P=760.051 Torr; 13 h;
参考文献
Song, Ren-Jie; Liu, Yu; Hu, Rui-Xiang; Liu, Yan-Yun; Wu, Ji-Cheng; Yang, Xu-Heng; Li, Jin-Heng
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1467 - 1473
反应条件
sulfuric acid
0.5 h; Heating / reflux;
参考文献
PHOTOBIOCHEM N.V.
Patent: WO2006/96053 A1, 2006 ;
Location in patent: Page/Page column 22 ;
参考文献
Roberts; Vogt
Journal of the American Chemical Society, 1956 , vol. 78, p. 4778,4780
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate in benzene
T=5 - 10°C; 1 h; Heating;
参考文献
Sharma, V. K.; Kumar, A.; Agarwal, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 11 p. 1153
反应条件
1: benzene / Heating
2: anhydrous potassium carbonate, sodium hydroxide, tetrabutylammonium hydrogensulphate / benzene / 1 h / 5 - 10 °C / Heating
View Scheme
参考文献
Sharma, V. K.; Kumar, A.; Agarwal, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 11 p. 1153
反应条件
sodium hydroxide in water
T=30°C; also aq. DMSO; Rate constantMechanism;
参考文献
Bowden, Keith; Bromley, Keith
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1990 , p. 2103 - 2109
