3-硝基-4-氟苯甲酰氯合成路线 （共 17 条）
反应条件
1: sodium azide / CH2Cl2; dimethylformamide / 20 °C 2: CH2Cl2; dimethylformamide / Heating View Scheme
参考文献
Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917
反应条件
hydrogenchloride; aluminium trichloride in di-isopropyl ether; benzene
参考文献
Janssen Pharmaceutica N.V.
Patent: US4943574 A1, 1990 ;
反应条件
in dichloromethane
T=0°C;
参考文献
PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2007/2742 A1, 2007 ;
Location in patent: Page/Page column 24; 30 ;
WO 2007/002742 A1
反应条件
1: 0 °C
2: dimethylformamide / 0 °C
View Scheme
参考文献
Cole, Andrew G.; Stroke, Ilana L.; Brescia, Marc-Raleigh; Simhadri, Srilatha; Zhang, Joan J.; Hussain, Zahid; Snider, Michael; Haskell, Christopher; Ribeiro, Sofia; Appell, Kenneth C.; Henderson, Ian; Webb, Maria L.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 1 p. 200 - 203
参考文献
Fosdick; Dodds
Journal of the American Chemical Society, 1943 , vol. 65, p. 2305
参考文献
Rouche
Bulletin de la Classe des Sciences, Academie Royale de Belgique, 1921 , vol. <5> 7, p. 536
Chem. Zentralbl., 1922 , vol. 93, # I p. 22
参考文献
Rouche
Bulletin de la Classe des Sciences, Academie Royale de Belgique, 1921 , vol. <5> 7, p. 536
Chem. Zentralbl., 1922 , vol. 93, # I p. 22
