4-羟基-3-硝基三氟甲苯合成路线 （共 18 条）
反应条件
sodium hydroxide in dimethyl sulfoxide T=20 - 25°C;
参考文献
Di, Chong-An; Li, Jing; Yu, Gui; Xiao, Yi; Guo, Yunlong; Liu, Yunqi; Qian, Xuhong; Zhu, Daoben
Organic Letters, 2008 , vol. 10, # 14 p. 3025 - 3028
反应条件
sodium hydroxide in hydrogenchloride; methanol
参考文献
Bayer Aktiengesellschaft
Patent: US4225731 A1, 1980 ;
反应条件
hydrogenchloride; potassium hydroxide
参考文献
Bayer Aktiengesellschaft
Patent: US4225731 A1, 1980 ;
反应条件
nitronium tetrafluoroborate in acetonitrile T=0°C; 1 h;
参考文献
Kozic, Jan; Novotna, Eva; Volkova, Marie; Stolarikova, Jirina; Trejtnar, Frantisek; Wsol, Vladimir; Vinsova, Jarmila
European Journal of Medicinal Chemistry, 2012 , vol. 56, p. 108 - 119
反应条件
potassium fluoride; anhydrous tetramethylammonium chloride in sulfolane T=180°C;
参考文献
Maggini, Michele; Passudetti, Margherita; Gonzales-Trueba, Guadalupe; Prato, Maurizio; Quintily, Ugo; Scorrano, Gianfranco
Journal of Organic Chemistry, 1991 , vol. 56, # 22 p. 6406 - 6411
反应条件
sulfuric acid; sodium nitrite anschliessendes Erhitzen mit CuSO4;
参考文献
Pettit; Tatlow
Journal of the Chemical Society, 1954 , p. 3852
Full Text Show Details
Jagupol'skii; Mospan
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1955 , vol. 21, p. 81,83
Chem.Abstr., 1955 , p. 8866
反应条件
sulfuric acid; water; nitric acid T=110°C;
参考文献
Jagupol'skii; Mospan
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1955 , vol. 21, p. 81,83
Chem.Abstr., 1955 , p. 8866
反应条件
hydrogen; palladium on activated charcoal in ethanol T=40°C; P=2068.65 Torr;
参考文献
Merial Limited; Meng, Charles Q.; Long, Alan; Huber, Scot; Gurrala, Srinivas Reddy; Wilkinson, Douglas Edward; Pacofsky, Gregory
Patent: US2014/142114 A1, 2014 ;
Location in patent: Paragraph 0859; 0860 ;
参考文献
SmithKline Beecham Corporation
Patent: US6262113 B1, 2001 ;
US 6262113 B1
参考文献
SmithKline Beecham Corporation
Patent: US5886044 A1, 1999 ;
US 5886044 A
