1: pyridine / 0.5 h / Ambient temperature 2: 95 percent / H2 / 10percent Pd(OH)2/C / methanol / 12 h 3: 92 percent / MS 4A, MeOTf / CH2Cl2 / 18 h / Ambient temperature 4: 1.) H2NNH2*H2O; 2.) DMAP / 1.) EtOH, 90 deg C, 24 h; 2.) pyridine, 12 h 5: 90 percent / NaOMe / methanol / 20 h / Ambient temperature View Scheme

1: 93 percent / toluene-p-sulfonic acid / dimethylformamide / 1.5 h / 70 °C / 12 Torr 2: 72 percent / mercury(II) cyanide, molecular sieve 3 Angstroem / acetonitrile / 24 h / Ambient temperature 3: 95 percent / KOH / dioxane 4: 92 percent / aq. 90percent acetic acid / 2 h / 85 °C 5: 92 percent / H2, 10percent Pd/C / methanol / Ambient temperature View Scheme

1: pyridine / 0.5 h / Ambient temperature 2: 95 percent / H2 / 10percent Pd(OH)2/C / methanol / 12 h 3: 92 percent / MS 4A, MeOTf / CH2Cl2 / 18 h / Ambient temperature 4: 1.) H2NNH2*H2O; 2.) DMAP / 1.) EtOH, 90 deg C, 24 h; 2.) pyridine, 12 h 5: 90 percent / NaOMe / methanol / 20 h / Ambient temperature View Scheme