1-(2-甲氧基苯基)乙胺合成路线 （共 33 条）
反应条件
1: 5 platinum on carbon; hydrogen / isopropanol acetate 2: 5 Pd(II)/C(eggshell); hydrogen / methanol / 24 h / 50 °C / 11251.1 Torr View Scheme
参考文献
Nugent, Thomas C.; Marinova, Sofiya M.
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-Z0768-FA, p. 153 - 166
参考文献
Chapman, Daniel T.; Crout, David H. G.; Mahmoudian, Mahmoud; Scopes, David I. C.; Smith, Paul W.
Chemical Communications, 1996 , # 21 p. 2415 - 2416
反应条件
(S)-(6-methoxy-2-naphthyl)glycolic acid in ethanol; water Title compound not separated from byproducts;
参考文献
Mereyala, Hari Babu; Koduru, Sreenivasulu Reddy; Cheemalapati, Venkata Narasimhaji
Tetrahedron Asymmetry, 2006 , vol. 17, # 2 p. 259 - 267
反应条件
ammonium acetate; sodium cyanoborohydride in methanol 96 h; Ambient temperature;
参考文献
Giardina; Marrazzo; Marucci; Grazia Piloni; Quaglia
Farmaco, 1991 , vol. 46, # 7-8 p. 861 - 872
反应条件
sodium hydroxide in dichloromethane; water
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C 1.2: 18 h / 20 °C 2.1: C19H23BNO3(1-)*H(1+); borane-THF / 1,4-dioxane / 72 h / |Inert atmosphere View Scheme
参考文献
Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327
反应条件
borane-THF; C19H23BNO3(1-)*H(1+) in 1,4-dioxane 72 h; Inert atmosphere; enantioselective reaction;
参考文献
Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327
反应条件
Multistep reaction. Title compound not separated from byproducts.;
参考文献
Dai, Xing; Nakai, Takashi; Romero, Jan A. C.; Fu, Gregory C.
Angewandte Chemie - International Edition, 2007 , vol. 46, # 23 p. 4367 - 4369
反应条件
lead(IV) acetate; hydrogenchloride 1.) CH2Cl2, MeOH, 0 deg C, 5 min, 2.) Et2O, RT, 15 h; Yield given. Multistep reaction;
参考文献
Yamauchi, Takayasu; Takahashi, Hiroshi; Higashiyama, Kimio
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 3 p. 384 - 389
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 456 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
