苄基-((E)-3-苯基-烯丙基)-胺合成路线 （共 35 条）
反应条件
Pt(COD)Cl2; bis[2-(diphenylphosphino)phenyl] ether in 1,4-dioxane
18 h; Heating;
参考文献
Utsunomiya, Masaru; Miyamoto, Yoshiki; Lpposhi, Junji; Ohshima, Takashi; Mashima, Kazushi
Organic Letters, 2007 , vol. 9, # 17 p. 3371 - 3374
反应条件
1: ethyl acetoacetate With n-butyllithium; sodium hydride in tetrahydrofuran; hexane
T=0°C; 0.166667 h;
2: (+/-) 3,5-dibenzyl[1,2,3]oxathiazolidine-2,2-dioxide in tetrahydrofuran; hexane
T=50°C; 16 h;
3: With hydrogenchloride in tetrahydrofuran; hexane
T=20°C; 2 h; Further stages.;
参考文献
Bower, John F.; Szeto, Peter; Gallagher, Timothy
Organic Letters, 2007 , vol. 9, # 23 p. 4909 - 4912
反应条件
sodium tetrahydroborate in methanol
0.25 h; Ambient temperature;
参考文献
Abdel-Magid, Ahmed F.; Carson, Kenneth G.; Harris, Bruce D.; Maryanoff, Cynthia A.; Shah, Rekha D.
Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3849 - 3862
反应条件
bis(η3-allyl-μ-chloropalladium(II)); (S,Rphos,R)-[(BINOL)(Et2N)P][4-Ph-oxazole-deriv.]ferrocene in dichloromethane
T=0°C; 7 h;
参考文献
You; Zhu; Luo; Hou; Dai
Journal of the American Chemical Society, 2001 , vol. 123, # 30 p. 7471 - 7472
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; C12H8O2PN(CH(CH3)C6H5)2 in tetrahydrofuran
T=25°C; 48 h;
参考文献
YALE UNIVERSITY
Patent: WO2004/24684 A2, 2004 ;
Location in patent: Page 14; 16-17 ;
反应条件
1: pyridine; 4-dimethylaminopyridine / tetrahydrofuran / 20 °C
2: [(η3-allyl)Pd(S-BINAP(S))]SbF6 / ethyl acetate / 18 h / -25 °C
View Scheme
参考文献
Faller; Wilt, Jeremy C.
Organic Letters, 2005 , vol. 7, # 4 p. 633 - 636
反应条件
bismuth; tetrabutylammomium bromide in acetonitrile
0.15 h; Ambient temperature;
参考文献
Bhuyan, Pulak J.; Prajapati, Dipak; Sandhu, Jagir S.
Tetrahedron Letters, 1993 , vol. 34, # 49 p. 7975 - 7976
反应条件
[(η3-allyl)Pd((S)-2-Ph2P-2'-Ph2P(S)-1,1'-binaphthyl)]SbF6 in ethyl acetate
T=-25°C; 18 h;
参考文献
Faller; Wilt, Jeremy C.
Organic Letters, 2005 , vol. 7, # 4 p. 633 - 636
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; rac-(1,1'-binaphthyl-2,2'-dioxy)PN(CHMePh)2 in tetrahydrofuran
16 h;
参考文献
YALE UNIVERSITY
Patent: WO2004/24684 A2, 2004 ;
Location in patent: Page 17-19 ;
反应条件
(S)-mesophore confined Pd(II) catalyst in tetrahydrofuran
T=40°C; Alkylation; Title compound not separated from byproducts;
参考文献
Johnson, Brian F. G.; Raynor, Stuart A.; Shephard, Douglas S.; Mashmeyer, Thomas; Thomas, John Meurig; Sankar, Gopinthar; Bromley, Stefen; Oldroyd, Richard; Gladden, Lynn; Mantle, Mike D.
Chemical Communications, 1999 , # 13 p. 1167 - 1168
