反应条件
1: With ammonia; benzotriazol-1-ol in methanol; N,N-dimethyl-formamide
T=20°C;
2: (1-(tert-butoxycarbonyl)-(4S)-fluoro-(2R)-pyrrolidinyl)acetic acid With N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide in N,N-dimethyl-formamide
T=20°C;
参考文献
MERCK and CO., INC.
Patent: WO2007/64553 A2, 2007 ;
Location in patent: Page/Page column 103 ;
WO 2007/064553 A2
