potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=100°C; Suzuki coupling; 17 h;

sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water T=95°C; 17 h;

1: triethylamine / dichloromethane / 6 h / 0 - 20 °C 2: palladium diacetate; tricyclopentyl-phosphine; potassium carbonate / toluene / 8 h / 95 °C / |Glovebox View Scheme

1: sodium acetate; hydroxylamine hydrochloride / methanol / 4 h / |Reflux 2: triethylamine / dichloromethane / 6 h / 0 - 20 °C 3: palladium diacetate; tricyclopentyl-phosphine; potassium carbonate / toluene / 8 h / 95 °C / |Glovebox View Scheme