反应条件
1: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 2 h;
2: With boric acid trimethyl ester in tetrahydrofuran; hexane
T=-78 - 20°C;
参考文献
Goodacre, Simon C.; Street, Leslie J.; Hallett, David J.; Crawforth, James M.; Kelly, Sarah; Owens, Andrew P.; Blackaby, Wesley P.; Lewis, Richard T.; Stanley, Joanna; Smith, Alison J.; Ferris, Pushpinder; Sohal, Bindi; Cook, Susan M.; Pike, Andrew; Brown, Nicola; Wafford, Keith A.; Marshall, George; Castro, Jose L.; Atack, John R.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 35 - 38