(R)-2-(1-(叔丁氧基羰基)哌啶-4-基)-2-(苄氧基羰基)乙酸合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol; water T=20°C; P=2585.74 Torr; 16 h;
参考文献
Shieh, Wen-Chung; Xue, Song; Reel, Noela; Wu, Raeann; Fitt, John; Repic, Oljan
Tetrahedron Asymmetry, 2001 , vol. 12, # 17 p. 2421 - 2425
反应条件
lithium hydroxide in methanol
T=20°C; 20 h;
参考文献
Shieh, Wen-Chung; Xue, Song; Reel, Noela; Wu, Raeann; Fitt, John; Repic, Oljan
Tetrahedron Asymmetry, 2001 , vol. 12, # 17 p. 2421 - 2425
反应条件
1: 61 percent / tetramethylguanidine / ethyl acetate / 42 h / 20 °C
2: H2 / [(R,R)-Me-BPE-Rh-COD]OTf / methanol / 72 h / 20 °C / 4654.33 Torr
3: 98 percent / 1N LiOH / methanol / 20 h / 20 °C
View Scheme
参考文献
Shieh, Wen-Chung; Xue, Song; Reel, Noela; Wu, Raeann; Fitt, John; Repic, Oljan
Tetrahedron Asymmetry, 2001 , vol. 12, # 17 p. 2421 - 2425
反应条件
1: 61 percent / tetramethylguanidine / ethyl acetate / 42 h / 20 °C
2: H2 / [(R,R)-Me-BPE-Rh-COD]OTf / methanol / 72 h / 20 °C / 4654.33 Torr
3: 98 percent / 1N LiOH / methanol / 20 h / 20 °C
View Scheme
参考文献
Shieh, Wen-Chung; Xue, Song; Reel, Noela; Wu, Raeann; Fitt, John; Repic, Oljan
Tetrahedron Asymmetry, 2001 , vol. 12, # 17 p. 2421 - 2425
反应条件
1: H2 / [(R,R)-Me-BPE-Rh-COD]OTf / methanol / 72 h / 20 °C / 4654.33 Torr
2: 98 percent / 1N LiOH / methanol / 20 h / 20 °C
View Scheme
参考文献
Shieh, Wen-Chung; Xue, Song; Reel, Noela; Wu, Raeann; Fitt, John; Repic, Oljan
Tetrahedron Asymmetry, 2001 , vol. 12, # 17 p. 2421 - 2425
