反应条件
1: 2-amino-1,3-propanediol With hydrogenchloride in methanol; water
T=20°C; 2 h;
2: 2,2-dimethoxy-propane With toluene-4-sulfonic acid in N,N-dimethyl-formamide
Inert atmosphere;
3: With triethylamine in N,N-dimethyl-formamide
0.166667 h;
参考文献
Jie, Yuanping; Livant, Peter; Li, Hui; Yang, Minmin; Zhu, Wei; Cammarata, Vince; Almond, Philip; Sullens, Tyler; Qin, Yu; Bakker, Eric
Journal of Organic Chemistry, 2010 , vol. 75, # 13 p. 4472 - 4479