1.1: sec-BuLi / tetrahydrofuran / 2 h / -78 °C 1.2: 86 percent / tetrahydrofuran / 1 h / -78 - 0 °C 2.1: Na2HPO4; m-chloroperbenzoic acid / CH2Cl2; CHCl3 / 1 h / 20 °C 3.1: 13.8 g / NaOH / methanol / 2 h 4.1: K2CO3; tetrabutylammonium iodide / dimethylformamide / 72 h / 20 °C 5.1: 1.45 g / aq. HCl / tetrahydrofuran / 1 h View Scheme

1.1: sec-BuLi / tetrahydrofuran / 2 h / -78 °C 1.2: 86 percent / tetrahydrofuran / 1 h / -78 - 0 °C 2.1: Na2HPO4; m-chloroperbenzoic acid / CH2Cl2; CHCl3 / 1 h / 20 °C 3.1: 13.8 g / NaOH / methanol / 2 h 4.1: K2CO3; tetrabutylammonium iodide / dimethylformamide / 72 h / 20 °C 5.1: 1.45 g / aq. HCl / tetrahydrofuran / 1 h 6.1: 85 percent / NaBH4 / tetrahydrofuran; propan-2-ol / 16 h / 20 °C View Scheme