2-(4-氯苄基氨基)乙醇合成路线 (共 6 条)
反应条件
1: T=40°C; 0.5 h; 2: With sulfuric acid T=150°C; 0.5 h;
参考文献
Neurosearch A/S
Patent: US6207662 B1, 2001 ;
反应条件
sodium tetrahydroborate in methanol
T=5 - 20°C;
参考文献
Chan; Laughton; Queener; Stevens
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2555 - 2564
反应条件
1: in ethanol
2: With sodium tetrahydroborate in methanol; ethanol
参考文献
NORTHWESTERN UNIVERSITY
Patent: WO2008/36294 A2, 2008 ;
Location in patent: Page/Page column 4; 5/8 ;
WO 2008/036294 A2
反应条件
sodium hydroxide in isopropyl alcohol
0.5 h; Heating;
参考文献
Audouze, Karine; Nielsen, Elsebet stergaard.; Peters, Dan
Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3089 - 3104
反应条件
1: NaHCO3 / methanol / 4 h / Heating
2: sodium borohydride / methanol / 5 - 20 °C
View Scheme
参考文献
Chan; Laughton; Queener; Stevens
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2555 - 2564
参考文献
Bayer Corporation
Patent: US6353006 B1, 2002 ;
Location in patent: Page column 95 ;
US 6353006 B1