3,4-二氯苯硼酸频那醇酯合成路线 （共 16 条）
反应条件
1.1: tetrafluoroboric acid / water / 0.17 h / 0 °C 1.2: 1 h / 0 °C 1.3: 2.5 h / 20 °C / |Inert atmosphere 2.1: diethyl ether / 4 h / 20 °C View Scheme
参考文献
Marciasini, Ludovic D.; Vaultier, Michel; Pucheault, Mathieu
Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1702 - 1705
反应条件
1.1: sec.-butyllithium / diethyl ether; hexane; cyclohexane / 1 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 °C / Inert atmosphere 2.1: cesium fluoride / dichloromethane; water / 16 h / 20 °C 3.1: tetrahydrofuran / 2 h / 20 °C 4.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 20 °C 5.1: Jone's reagent / acetone / 0 - 20 °C 6.1: chlorosulfonic acid / dichloromethane / 0.75 h / 20 °C 7.1: sodium acetate / ethanol / 15 h / Reflux 7.2: 20 h / 20 °C / 760.05 Torr View Scheme
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
反应条件
copper(l) iodide; 1,10-phenanthroline; potassium iodide in methanol; water T=80°C; 1 h; High pressure;
参考文献
Organic Letters, , vol. 15, # 1 p. 140 - 143
反应条件
1.1: sec.-butyllithium / diethyl ether; hexane; cyclohexane / 1 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 °C / Inert atmosphere 2.1: cesium fluoride / dichloromethane; water / 16 h / 20 °C 3.1: tetrahydrofuran / 2 h / 20 °C 4.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 20 °C 5.1: Jone's reagent / acetone / 0 - 20 °C 6.1: chlorosulfonic acid / dichloromethane / 0.75 h / 20 °C View Scheme
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
反应条件
potassium phosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in hexane; N,N-dimethyl-formamide
T=60°C; 2 h;
参考文献
Kikuchi, Takao; Nobuta, Yusuke; Umeda, Junko; Yamamoto, Yasunori; Ishiyama, Tatsuo; Miyaura, Norio
Tetrahedron, 2008 , vol. 64, # 22 p. 4967 - 4971
反应条件
1.1: sec.-butyllithium / diethyl ether; hexane; cyclohexane / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: cesium fluoride / dichloromethane; water / 16 h / 20 °C
3.1: tetrahydrofuran / 2 h / 20 °C
4.1: dihydrogen peroxide; sodium hydroxide / water / 0 - 20 °C
5.1: Jone's reagent / acetone / 0 - 20 °C
6.1: chlorosulfonic acid / dichloromethane / 0.75 h / 20 °C
View Scheme
参考文献
Roesner, Stefan; Casatejada, Javier Mansilla; Elford, Tim G.; Sonawane, Ravindra P.; Aggarwal, Varinder K.
Organic Letters, 2011 , vol. 13, # 21 p. 5740 - 5743
