2,6-二碘-4-[(2-甲基-1-苯并呋喃-3-基)甲基]苯酚合成路线 （共 2 条）
反应条件
1: 63 percent / SnCl4 / CH2Cl2 / 5 °C
2: NaBH4; ZnI2 / 1,2-dichloro-ethane / 2.25 h / 70 °C
3: pyridine hydrochloride / 2 h / 190 °C
4: 429 g / ICI*tetramethylammonium chloride; morpholine / methanol / 1 h / 20 - 30 °C
View Scheme
参考文献
Carlsson, Bo; Singh; Temciuc, Marcel; Nilsson, Stefan; Li, Yi-Lin; Mellin, Charlotta; Malm, Johan
Journal of Medicinal Chemistry, 2002 , vol. 45, # 3 p. 623 - 630
反应条件
1: 63 percent / SnCl4 / CH2Cl2 / 5 °C
2: NaBH4; ZnI2 / 1,2-dichloro-ethane / 2.25 h / 70 °C
3: pyridine hydrochloride / 2 h / 190 °C
4: 429 g / ICI*tetramethylammonium chloride; morpholine / methanol / 1 h / 20 - 30 °C
View Scheme
参考文献
Carlsson, Bo; Singh; Temciuc, Marcel; Nilsson, Stefan; Li, Yi-Lin; Mellin, Charlotta; Malm, Johan
Journal of Medicinal Chemistry, 2002 , vol. 45, # 3 p. 623 - 630
